EXPERT OF THE MONTH

Juan Carlos Kaski (UK)
Juan-Carlos Kaski is Emeritus Professor of Cardiovascular Science and the immediate past-director of the Cardiovascular and Cell Sciences Research Institute at St George’s, University of London, UK. His...

IN THE LITERATURE THIS WEEK
Management for Stable Ischemic Heart Disease: Part 1


Currently, the management of stable coronary artery disease is based upon the idea of flow-limiting atherosclerotic obstructions. Hence, revascularisation has been a focus due to obstructions being viewed as the cause of angina and myocardial ischemia. However, many randomised controlled trials (RCTs) have proven that revascularisation does not reduce mortality…..
Latest featured publications
Heart failure


Management for Stable Ischemic Heart Disease: Part 1
Currently, the management of stable coronary artery disease is based upon the idea of flow-limiting atherosclerotic obstructions. Hence, revascularisation has been a focus due to obstructions being viewed as the cause of angina and myocardial ischemia. However, many randomised controlled trials...
Heart failure


Management for Stable Ischemic Heart Disease: Part 2
The ISCHEMIA (International Study of Comparative Health Effectiveness with Medical and Invasive Approaches) found that invasive approaches do not benefit endpoints such as cardiovascular death, myocardial infarction or hospitalisation for heart failure. There was also only a modest improvement in quality...
Angina


Coronary microvascular angina: a review
Out of the patients who undergo coronary angiography due to angina and myocardial ischemia, up to 70% do not have obstructive coronary disease. For many, coronary microvascular angina as a cause of dysfunctional coronary microcirculation is often the reason behind this....
Angina


Prediction models in angina: a review
The assessment of pre-test probability is an important gatekeeper for knowing which patients to select in diagnostic testing for coronary artery disease. The European Society of Cardiology (also known as The ESC) recommends evaluating pre-test probability from factors such as sex,...
Angina


Angina resolution and percutaneous coronary intervention: a review
Percutaneous coronary intervention, PCI, aims to relieve angina symptoms in patients with stable coronary artery disease. However, predicting symptom resolution post-percutaneous coronary intervention has proven difficult as the predictors are ill-defined. Furthermore, there is little evidence which supports the fact that...
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Adjusting guideline-directed medical therapy to the patient profile<
The slide above illustrates the role of PPARα, PPARβ/δ and PPARγ as key regulators of lipid metabolism, inflammation and glucose metabolism....
Angina
Best practices for the management of post-PCI angina<
The slide above illustrates the role of PPARα, PPARβ/δ and PPARγ as key regulators of lipid metabolism, inflammation and glucose metabolism....
Latest pubmed articles
- A systematic review of enrolment criteria and treatment efficacy for microvascular angina
- Treatment of microvascular angina pectoris by activating blood circulation to remove blood stasis: A systematic review and meta-analysis
- A recurrent typical angina pectoris without any finding in coronary angiography: Microvascular angina
- Generation of a medicine food homology formula and its likely mechanism in treatment of microvascular angina
- Zibotentan in Microvascular Angina: A Randomized, Placebo-Controlled, Crossover Trial
- The Diagnostic Value of ECG Characteristics for Vasospastic and Microvascular Angina: A Systematic Review
- Inflammatory biomarkers in cardiac syndrome X: a systematic review and meta-analysis
- Positron emission tomography assessment of coronary microvascular angina in patients with angina and nonobstructive coronary artery disease
- Coronary microvascular dysfunction assessment: A comparative analysis of procedural aspects
- "The INOCA-IT: Rationale and design of a multicenter registry investigating ischemia in patients with non-obstructive coronary artery (INOCA) disease in Italy"
- Pilot Study of Supervised Exercise and Intensive Medical Therapy in Patients With Ischemia With No Evidence of Obstructive Coronary Artery Disease and Coronary Microvascular Dysfunction
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