Currently, the management of stable coronary artery disease is based upon the idea of flow-limiting atherosclerotic obstructions. Hence, revascularisation has been a focus due to obstructions being viewed as the cause of angina and myocardial ischemia. However, many randomised controlled trials...

The ISCHEMIA (International Study of Comparative Health Effectiveness with Medical and Invasive Approaches) found that invasive approaches do not benefit endpoints such as cardiovascular death, myocardial infarction or hospitalisation for heart failure. There was also only a modest improvement in quality...

Out of the patients who undergo coronary angiography due to angina and myocardial ischemia, up to 70% do not have obstructive coronary disease. For many, coronary microvascular angina as a cause of dysfunctional coronary microcirculation is often the reason behind this....

The assessment of pre-test probability is an important gatekeeper for knowing which patients to select in diagnostic testing for coronary artery disease. The European Society of Cardiology (also known as The ESC) recommends evaluating pre-test probability from factors such as sex,...

Percutaneous coronary intervention, PCI, aims to relieve angina symptoms in patients with stable coronary artery disease. However, predicting symptom resolution post-percutaneous coronary intervention has proven difficult as the predictors are ill-defined. Furthermore, there is little evidence which supports the fact that...