The application of Gensini score and IL-1ra in assessing the condition and prognosis of patients with coronary artery disease

CHD is characterised by ischemic lesions and hypoxia, and one of its most notable symptoms is angina. As such, 175 CHD patients were divided into 3 groups: stable angina group, unstable angina group, and acute myocardial infarction group. As their conditions evolved, their Gensini scores and IL-1ra levels (amongst other scales, e.g. GRACE score and troponin levels) were recorded.
Authors of this study found a positive correlation between CHD patients’ prognosis and Gensini scores and IL-1ra levels. As their conditions worsened, their Gensini scores and IL-1ra levels increased.
Take-home message: According to the results of this study, Gensini scores and IL-1ra levels are valuable to the monitoring of disease severity and evolution: as CHD patients’ condition worsens, both factors increase. They could thus be of great clinical importance to prognostic evaluation and major adverse cardiac event (MACE) prevention in patients with CHD