CHD is characterised by ischemic lesions and hypoxia, and one of its most notable symptoms is angina. As such, 175 CHD patients were divided into 3 groups: stable angina group, unstable angina group, and acute myocardial infarction group. As their conditions evolved, their Gensini scores and IL-1ra levels (amongst other scales, e.g. GRACE score and troponin levels) were recorded.
Authors of this study found a positive correlation between CHD patients’ prognosis and Gensini scores and IL-1ra levels. As their conditions worsened, their Gensini scores and IL-1ra levels increased. Take-home message: According to the results of this study, Gensini scores and IL-1ra levels are valuable to the monitoring of disease severity and evolution: as CHD patients’ condition worsens, both factors increase. They could thus be of great clinical importance to prognostic evaluation and major adverse cardiac event (MACE) prevention in patients with CHD