Safety and Efficacy of Ivabradine in Chronic Heart Failure: a review

This study analysed 220 participants to understand whether Ivabradine is safe and efficacious in patients with chronic heart failure. Ivabradine is an antianginal drug, used as an alternative to beta blockers. Using this drug demonstrated improved symptoms in patients with a heart rate above 70 beats per minute who were optimized for heart failure treatment. Heart rate is seen to return to normal after Ivabradine intake, specifically in groups aged 35 to 40. Adverse effects were not seen in the population of participants, but some possible effects include bradycardia, hypertension and luminous phenomenon.

This review by Andhi N et al. aimed to review the safety and efficacy of the antianginal drug Ivabradine.

Key learnings

Among the Ca+2 channel blocker drugs available, Ivabradine has demonstrated itself to be vital for the management of chronic heart failure. It works by decreasing the heart rate in such patients, and although side effects are possible, they can be avoided with dose adjustments.