From coronary physiology to precision medicine

Coronary physiological assessment is generally widely applied in the assessment of epicardial coronary lesions, with fractional flow reserve being viewed as the gold standard method. It is used to select whether epicardial coronary lesions require revascularization. However, this paper also explored the use of other techniques, such as hyperaemic stenosis resistance, instantaneous hyperaemic diastolic velocity pressure slope, wave intensity analysis and more. The strengths and weaknesses of these assessments were discussed, drawing towards the overall conclusion of the benefits of precision medicine. By individualising the different therapeutic strategies used for every patient, cardiovascular medicine can move towards the more accurate potential of precision medicine.

This review by Maitre-Ballesteros L et al. aimed to review the role of precision medicine in chronic coronary syndrome assessment.

Key learnings:

A future focus is needed into implementing precision method into the cardiovascular field, to improve the assessments used for coronary physiology in individual patients. This will allow for patients to receive greater benefit from their condition treatment and symptom management.